inst/NEWS.md

In SONGDONGYUAN1994/PseudotimeDE: Inference of differential gene expression along cell pseudotime with well-calibrated p-values from single-cell RNA sequencing data

Changes in PseudotimeDE

Version 0.99.0 (First Bioconductor Submission)

New Features

• Introduced pseudotimeDE(), a function for performing differential expression analysis along pseudotime using GAM models.
• Added plotCurve() for visualizing gene expression trends along pseudotime.
• Implemented plotUncertainty() to display pseudotime variability across subsamples.
• Included runPseudotimeDE(), a wrapper for running pseudotimeDE() on multiple genes efficiently.

Significant User-Visible Changes

• Ensured compatibility with SingleCellExperiment and Seurat objects.
• Optimized computational performance with parallel processing (BiocParallel).

SONGDONGYUAN1994/PseudotimeDE documentation built on Feb. 11, 2025, 4:38 p.m.