kozak_IR_ranking: Rank kozak initiation sequences

kozak_IR_rankingR Documentation

Rank kozak initiation sequences

Description

Defined as region (-4, -1) relative to TIS

Usage

kozak_IR_ranking(cds_k, mrna, dt.ir, faFile, group.min = 10, species = "human")

Arguments

cds_k

cds ranges (GRangesList)

mrna

mrna ranges (GRangesList)

dt.ir

data.table with a column called IR, initiation rate

faFile

FaFile, BSgenome, fasta/index file path or an ORFik experiment. This file is usually used to find the transcript sequences from some GRangesList.

group.min

numeric, default 10. Minimum transcripts per initation group to be included

species

("human"), which species to use, currently supports human (Homo sapiens), zebrafish (Danio rerio) and mouse (Mus musculus). Both scientific or common name for these species will work. You can also specify a pfm for your own species. Syntax of pfm is an rectangular integer matrix, where all columns must sum to the same value, normally 100. See example for more information. Rows are in order: c("A", "C", "G", "T")

Value

a ggplot grid object


Roleren/ORFik documentation built on Oct. 19, 2024, 7:37 a.m.