tableEdges: Tabulate the number of edges between annotations within a...

In alakazam: Immunoglobulin Clonal Lineage and Diversity Analysis

Tabulate the number of edges between annotations within a lineage tree

Description

tableEdges creates a table of the total number of connections (edges) for each unique pair of annotations within a tree over all nodes.

Usage

tableEdges(graph, field, indirect = FALSE, exclude = NULL)

Arguments

graph	igraph object containing an annotated lineage tree.
field	string defining the annotation field to count.
indirect	if FALSE count direct connections (edges) only. If TRUE walk through any nodes with annotations specified in the argument to count indirect connections. Specifying indirect=TRUE with exclude=NULL will have no effect.
exclude	vector of strings defining field values to exclude from counts. Edges that either start or end with the specified annotations will not be counted. If NULL count all edges.

Value

A data.frame defining total annotation connections in the tree with columns:

• parent: parent annotation

• child: child annotation

• count: count of edges for the parent-child relationship

See Also

See testEdges for performed a permutation test on edge relationships.

Examples

# Define example graph
graph <- ExampleTrees[[23]]

# Count direct edges between isotypes including inferred nodes
tableEdges(graph, "c_call")

# Count direct edges excluding edges to and from germline and inferred nodes
tableEdges(graph, "c_call", exclude=c("Germline", NA))

# Count indirect edges walking through germline and inferred nodes
tableEdges(graph, "c_call", indirect=TRUE, exclude=c("Germline", NA))

alakazam documentation built on Sept. 30, 2023, 9:07 a.m.