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A novel feature-wise normalization method based on a zero-inflated negative binomial model. This method assumes that the effects of sequencing depth vary for each taxon on their mean and also incorporates a rational link of zero probability and taxon dispersion as a function of sequencing depth. Ziyue Wang, Dillon Lloyd, Shanshan Zhao, Alison Motsinger-Reif (2023) <doi:10.1101/2023.10.31.563648>.
Package details |
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Author | Ziyue Wang [aut], Dillon Lloyd [aut, cre, cph], Shanshan Zhao [aut, ctb], Alison Motsinger-Reif [aut, ctb] |
Bioconductor views | Metagenomics Microbiome Normalization Sequencing Visualization |
Maintainer | Dillon Lloyd <dtlloyd@ncsu.edu> |
License | GPL-3 |
Version | 2.4 |
URL | https://github.com/wangziyue57/TaxaNorm |
Package repository | View on CRAN |
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