signeR: Empirical Bayesian approach to mutational signature discovery

The signeR package provides an empirical Bayesian approach to mutational signature discovery. It is designed to analyze single nucleotide variaton (SNV) counts in cancer genomes, but can also be applied to other features as well. Functionalities to characterize signatures or genome samples according to exposure patterns are also provided.

Package details

AuthorRafael Rosales, Rodrigo Drummond, Renan Valieris, Israel Tojal da Silva
Bioconductor views GenomicVariation SomaticMutation StatisticalMethod Visualization
MaintainerRenan Valieris <renan.valieris@accamargo.org.br>
LicenseGPL-3
Version1.16.0
URL https://github.com/rvalieris/signeR
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("signeR")

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signeR documentation built on Nov. 8, 2020, 8:08 p.m.