gemini: GEMINI: Variational inference approach to infer genetic interactions from pairwise CRISPR screens

GEMINI uses log-fold changes to model sample-dependent and independent effects, and uses a variational Bayes approach to infer these effects. The inferred effects are used to score and identify genetic interactions, such as lethality and recovery. More details can be found in Zamanighomi et al. 2019 (in press).

Package details

AuthorMahdi Zamanighomi [aut], Sidharth Jain [aut, cre]
Bioconductor views Bayesian CRISPR DataImport Software
MaintainerSidharth Jain <sidharthsjain@gmail.com>
LicenseBSD_3_clause + file LICENSE
Version1.4.0
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("gemini")

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gemini documentation built on Nov. 8, 2020, 8:22 p.m.