For single cell RNA-seq data collected from more than one subject (e.g. biological sample or technical replicates), this package contains tools to summarize single cell gene expression profiles at the level of subject. A SingleCellExperiment object is taken as input and converted to a list of SummarizedExperiment objects, where each list element corresponds to an assigned cell type. The SummarizedExperiment objects contain aggregate gene-by-subject count matrices and inter-subject column metadata for individual subjects that can be processed using downstream bulk RNA-seq tools.
Package details |
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Author | Jason Ratcliff [aut, cre] (<https://orcid.org/0000-0001-7079-334X>), Andrew Thurman [aut], Michael Chimenti [ctb], Alejandro Pezzulo [ctb] |
Bioconductor views | DifferentialExpression GeneExpression RNASeq SingleCell Software Transcription Transcriptomics |
Maintainer | Jason Ratcliff <jason-ratcliff@uiowa.edu> |
License | GPL-3 |
Version | 1.0.0 |
URL | https://github.com/jasonratcliff/aggregateBioVar |
Package repository | View on Bioconductor |
Installation |
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