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RnaSeqSampleSize package provides a sample size calculation method based on negative binomial model and the exact test for assessing differential expression analysis of RNA-seq data. It controls FDR for multiple testing and utilizes the average read count and dispersion distributions from real data to estimate a more reliable sample size. It is also equipped with several unique features, including estimation for interested genes or pathway, power curve visualization, and parameter optimization.
Package details |
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Author | Shilin Zhao Developer [aut, cre], Chung-I Li Developer [aut], Yan Guo Developer [aut], Quanhu Sheng Developer [aut], Yu Shyr Developer [aut] |
Bioconductor views | DifferentialExpression ExperimentalDesign GeneExpression ImmunoOncology RNASeq Sequencing |
Maintainer | Shilin Zhao Developer <zhaoshilin@gmail.com> |
License | GPL (>= 2) |
Version | 2.0.0 |
Package repository | View on Bioconductor |
Installation |
Install the latest version of this package by entering the following in R:
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