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######################################################
## GEOsearch ##
## Interactive User Interface ##
## UI File ##
## Author:Zhicheng Ji, Hongkai Ji ##
## Maintainer:Zhicheng Ji (zji4@jhu.edu) ##
######################################################
shinyUI(
pageWithSidebar(
headerPanel('GEOsearch: Extendable Search Engine for Gene Expression Omnibus'),
sidebarPanel(
wellPanel(
radioButtons("Mainmenu","Main Menu",list("Perform Search"="search","Key Word Enrichment"="keyword","Sample Details"="sample","Batch Download"="batch"))
),
conditionalPanel(condition="input.Mainmenu=='search'",
wellPanel(
h4("Search GEO"),
radioButtons("searchoption","",list("Traditional Search"="Traditional","Extended Search"="Expand")),
checkboxInput("searchGSMTF","In addition to GSE series, also search GSM samples (this step may take a long time for extended search)",value=FALSE),
conditionalPanel(condition="input.searchoption=='Expand'",
selectizeInput("searchexpandselectspecies","Select species in which gene alias will be searched",choices=c("Anopheles","Arabidopsis","Bovine","Worm","Canine","Fly","Zebrafish","E coli strain K12","E coli strain Sakai","Chicken","Human","Mouse","Rhesus","Malaria","Chimp","Rat","Yeast","Pig","Xenopus"),selected=c("Human","Mouse"),multiple=T),
helpText("Expand search will search all possible gene alias in the database. Search speed is slower for more species chosen.")
),
textInput("searchterm","Enter Search Term"),
actionButton("searchbutton","Start Search")
),
wellPanel(
h4("Download"),
checkboxInput("searchdownloadselectedparttf","Download Selected Part",value=FALSE),
downloadButton("searchdownloadbutton","Download Search Results for GSE series"),
conditionalPanel(condition="input.searchGSMTF=='1'",
checkboxInput("searchdownloadGSMselectedparttf","Download Selected Part",value=FALSE),
downloadButton("searchdownloadGSMbutton","Download Search Results for GSM samples")
)
)
),
conditionalPanel(condition="input.Mainmenu=='keyword'",
wellPanel(
h4("Key Word Enrichment Analysis"),
checkboxGroupInput("keywordselectterm","Include Following Information",choices = list("Disease"="disease","Cell Type"="celltype","Tissue"="tissue"),selected = c("disease","celltype","tissue"))
),
wellPanel(
h4("Download Results"),
downloadButton("keyworddownloadbuttonkeyword","Download Keyword Table"),
hr(),
checkboxInput("keyworddownloadselectedparttf","Download Selected Part",value=FALSE),
downloadButton("keyworddownloadbuttontable","Download Search Results")
)
),
conditionalPanel(condition="input.Mainmenu=='sample'",
wellPanel(
h4("Sample Details"),
radioButtons("sampleselectmethod","",list("Choose from selected GSE in step 1"="select1","Choose from selected GSE in step 2"="select2","Enter new GSE"="new")),
uiOutput("sampleselectui"),
actionButton("samplesearchbutton","Search Samples")
),
wellPanel(
h4("Download"),
checkboxInput("sampledownloadselectedparttf","Download Selected Part",value=FALSE),
downloadButton("sampledownloadbutton","Download Search Results")
)
),
conditionalPanel(condition="input.Mainmenu=='batch'",
wellPanel(
helpText("Before running this function, see instructions on the right."),
helpText("Multiple GSE or GSM name should be separated by ;"),
textInput("Batchinputtext","Enter GSE or GSM name"),
textInput("Batchinputpath","Specify the download path of the shell file","./"),
actionButton("Batchrunbutton","Make Shell File"),
downloadButton("Batchdownloadbutton","Download Shell File")
)
)
,width=3),
mainPanel(
conditionalPanel(condition="input.Mainmenu=='search'",
uiOutput("searchshowtableui")
),
conditionalPanel(condition="input.Mainmenu=='keyword'",
tabsetPanel(
tabPanel("Key Word",DT::dataTableOutput("keywordshowkeyword")),
tabPanel("Selected GSE",DT::dataTableOutput("keywordshowselectsample"))
)
),
conditionalPanel(condition="input.Mainmenu=='sample'",
DT::dataTableOutput("sampleshowtable")
),
conditionalPanel(condition="input.Mainmenu=='batch'",
wellPanel(
p("This function will return a shell file that will automatically download all the SRA files of the GSE or GSM if run."),
p("The shell file must be run on user's own Linux/Unix computer with wget installed."),
p("Note that GSE series with lots of samples will take the function a long time to finish. Use with care.")
),
h4("Shell File:"),
verbatimTextOutput("showbatchdownloadres")
)
)
))
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